مقایسه اثر ویتامینB1 در‏درمان دیسمنوره او‏لیه با ایبوپروفن در‏دختران جوان شهرستان یزد در سال 1381

Introduction: This study was performed in order to compare the efficacy of vitamin B1and Iboprofen in the treatment of primary dysmenorrhea. Methods: 180 women aged between 11-17 years with primary dysmenorrhea were divided to 2 groups: Group A: (n: 60) received 100mg vit B1 daily in leuteal phase for 3 months . Grope B :( n: 60) Received 400mg Ibuprofen 3 times/day for 5days (3 days before and 2 days after start of menses) for 3 months. Results: 80% of group A and 88.4% of group B were treated as compared to control (P=0001 ), but in group B, side effects were more and the regimen was less tolerated as compared to group A. Conclusion: Vit B (Thiamine) is well tolerated and effective drug without side effects in primary dysmenorrhea.